PRESENTERS: Michael W. Hart, DVM, MS, DACLAM, University Veterinarian and Director, Division of Animal Resources, Georgia State University; and Rex A. Howard, DVM, DACLAM, Assistant Director of Clinical Services, Division of Animal Resources, Georgia State University.
OVERVIEW: The mammalian phenotype is largely driven by the combination of host and microbiome genes. The microbiomes of free-living organisms (including wild mice and humans) co-evolved with their respective hosts over thousands of years by natural selection, creating a symbiotic host-microbe relationship integral to host physiology. The laboratory mouse microbiome evolved over much shorter periods in a sanitized and restrictive environment devoid of numerous microorganisms. For the past several years, one of Georgia State University's (GSU) investigators (who studies inflammation and translational immunology) has had an ongoing study concerning the "wilding" of the laboratory mouse gut microbiota. We will discuss the mechanisms of "wilding" utilized, the success of the mechanisms realized (shift in gut microbiota and immune phenotype), applications of the model, and challenges along the way. Moderated by Cindy A. Buckmaster, PhD, CMAR, RLATG. CONTINUING EDUCATION (CE): This webinar meets AALAS and CALAS requirements for 1.00 hour of CE and can be used elsewhere where accepted. A certificate of attendance will be emailed to all attendees within a few hours after the webinar concludes.
Registration closes Wednesday, August 30 at 5:00PM Eastern